/What are the clinical manifestations of nervous system damag

What are the clinical manifestations of nervous system damag

author:admin       pubdate:2017-08-11 16:05

The neuromuscular system symptoms in the early stage of CKD may have insomnia, inattention, memory loss and so on. With the development of the disease often respond apathy, convulsions, hallucinations, drowsiness, coma, mental abnormalities. Peripheral neuropathy is common. Hypocalcemia, hyperphosphatemia, active vitamin D deficiency can induce secondary hyperparathyroidism (PHPT); these factors lead to renal osteodystrophy (i.e. renal osteodystrophy), including osteitis fibrosa (high turnover bone disease), osteomalacia (low turnover bone), bone formation, osteoporosis and mixed bone disease.

(1) psychiatric symptoms: chronic renal insufficiency in patients with fatigue, concentration, apathy and irritability, irritability, memory loss, directional force decline, slow thinking, slow response, reduced efficiency, increased with severe renal dysfunction. A blood disorder, hallucinations, hallucinations. Visual hallucinations or delusions, obsessive fear (such as the face of horror of death), severe bleeding. Personality separation sleepiness.

(2) consciousness: severe renal dysfunction can occur in patients with disorders of consciousness, lethargy, delirium, stupor and coma. Hypermyotonia state was to cortex (upper limb elbow and wrist flexion, straight leg) or decerebrate rigidity (upper and lower limbs unbend, hand varus).

(3): myoclonic twitch, tetanic spasm - appear late in hemodialysis patients with chronic renal failure due to imbalance syndrome, nausea, vomiting, headache, seizures or seizures. (4) involuntary movement: flapping tremor: This is a characteristic symptom of metabolic encephalopathy, in encephalopathy early, for the performance of the two upper limbs unbend, flexion, wrist and fingers to separate the fingers around non-stop swing, fast without rhythm, bird like wings to fly with lower limbs may also appear similar. The upper limb tremor in asterixis before the advent of the constant amplitude irregular tremor, and flapping tremor alternately there. The muscle bundles, or myoclonus: a limb muscle of one side or both sides appear suddenly rapid, irregular muscle twitching, metabolic encephalopathy are common symptoms.

(5) other brain symptoms such as paralysis, aphasia, hemiplegia, paraplegia, ascending paralysis, ataxia and so on.

(6) cranial nerve and brainstem symptoms such as olfactory nerve caused by olfactory hallucination, olfactory loss; optic neuropathy caused by the absence of vision, vision loss, hemianopia, loss of vision (i.e. uremic amaurosis), diplopia, paralysis of extraocular muscle, nystagmus; facial nerve lesions can cause facial weakness, tongue muscle weak.

(7) meningeal symptoms: headache, neck resistance and positive Kerning sign and other meningeal irritation sign

(8) peripheral polyneuropathy: peripheral polyneuropathy occurred in the central lesion before. More performance for the lower limb, distal symmetrical sensory neuropathy, a sock shaped distribution. "Restless leg syndrome" is an early manifestation, patients with lower leg unspeakable discomfort, formication, pain pain that night, after walking activities or symptoms may disappear. Often accompanied by motor nerve conduction velocity and muscle tremor. Some patients feel hot feet, called "burning feet syndrome", many appeared after the restless legs syndrome. The progression of the disease can appear to reduce vibration, Achilles tendon reflex and knee tendon reflex. Then the muscle atrophy, proximal muscle weakness and severe paralyzed limbs.

(9) autonomic disorders: the performance of miotic, thin and little saliva, dry mouth, tachycardia or slow skin sweat or dry.



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